MMP8 Protein (AA 21-465) (His tag)
Quick Overview for MMP8 Protein (AA 21-465) (His tag) (ABIN7275273)
Target
See all MMP8 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 21-465
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Purification tag / Conjugate
- This MMP8 protein is labelled with His tag.
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Purpose
- Mouse MMP-8 Protein (active form)
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Sequence
- Phe21-Ser465
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Characteristics
- Recombinant Mouse MMP-8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe21-Ser465.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse MMP-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2. The specific activity is > 400 pmoles/min/ug.,The purity of Mouse MMP-8 is greater than 95% as determined by SEC-HPLC.
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Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 21-467) (Active) protein (His tag)
MMP8 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) proteinMMP8 Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 1-467) protein (GST tag)MMP8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 21-467) protein (His tag)MMP8 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in 20 mM MES, 150 mM NaCl ( pH 5.5).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
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Alternative Name
- MMP-8
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Background
- Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was significantly associated with low HCS.
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Molecular Weight
- 51.9 kDa. Due to glycosylation, the protein migrates to 65-80 kDa based on Bis-Tris PAGE result.
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UniProt
- O70138
Target
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