NCR1 Protein (AA 22-254) (Biotin,His tag)

Catalog No. ABIN7275349

This Recombinant NCR1 protein is expressed in HEK-293 Cells.

Quick Overview for NCR1 Protein (AA 22-254) (Biotin,His tag) (ABIN7275349)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 22-254

Purification tag / Conjugate: This NCR1 protein is labelled with Biotin,His tag.

Purpose: Biotinylated Human NKp46/NCR1/CD335 Protein (Primary Amine Labeling)

Sequence: Gln22-Asn254

Characteristics: Recombinant Biotinylated Human NKp46/NCR1/CD335 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the N-Terminus.It contains Gln22-Asn254.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Immobilized Biotinylated Human NKp46, His Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-NKp46 Antibody, hFc Tag with the EC50 of 19.7ng/ml determined by ELISA.,Biotinylated Human NKp46 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Biotinylated Human NKp46 is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: NKp46

Background: NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.

Molecular Weight: 27.5 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Bis-Tris PAGE result.

Pathways: Regulation of Leukocyte Mediated Immunity