NOTCH4 Protein (AA 1042-1441) (His tag)

Catalog No. ABIN7275367

This Recombinant NOTCH4 protein is expressed in HEK-293 Cells.

Quick Overview for NOTCH4 Protein (AA 1042-1441) (His tag) (ABIN7275367)

Target: NOTCH4 (Notch 4 (NOTCH4))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 1042-1441

Purification tag / Conjugate: This NOTCH4 protein is labelled with His tag.

Purpose: Mouse Notch 4 Protein

Sequence: Glu1042-Leu1441

Characteristics: Recombinant Mouse Notch 4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu1042-Leu1441.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse Notch 4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse Notch 4 is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PB, 500 mM NaCl, 10 % Glycerol ( pH 7.0).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: NOTCH4 (Notch 4 (NOTCH4))

Alternative Name: Notch 4

Background: The Notch signaling pathway is important for cell-cell communication, it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells.

Molecular Weight: 42.91 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

UniProt: P31695

Pathways: Notch Signaling