PKLR Protein (AA 20-105) (hFc Tag)
Quick Overview for PKLR Protein (AA 20-105) (hFc Tag) (ABIN7275451)
Target
See all PKLR ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 20-105
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Purification tag / Conjugate
- This PKLR protein is labelled with hFc Tag.
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Purpose
- Mouse PK-1/PROK1 Protein
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Sequence
- Ala20-Phe105
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Characteristics
- Recombinant Mouse PK-1/PROK1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ala20-Phe105.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse PK-1/PROK1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
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Alternative Name
- PK-1
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Background
- PK-1 (Ac10) is a baculovirus-encoded serine/threonine kinase,a pk-1 knockout AcMNPV failed to produce infectious progeny, while the pk-1 repair virus could rescue this defect.the kinase activity of PK-1 is essential in regulating viral propagation. Electron microscopy revealed that pk-1 deletion affected the formation of normal nucleocapsids.PK-1 appears to phosphorylate some viral or cellular proteins that are essential for DNA packaging to regulate nucleocapsid assembly.
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Molecular Weight
- 36.4 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Bis-Tris PAGE result.
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UniProt
- Q14A28
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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