MAG Protein (AA 20-516) (hFc Tag)
Quick Overview for MAG Protein (AA 20-516) (hFc Tag) (ABIN7275597)
Target
See all MAG ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 20-516
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Purification tag / Conjugate
- This MAG protein is labelled with hFc Tag.
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Purpose
- Human Siglec-4a/MAG Protein
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Sequence
- Gly20-Pro516
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Characteristics
- Recombinant Human Siglec-4a/MAG Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gly20-Pro516.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human Siglec-4a, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-4a Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA (QC Test).,Human Siglec-4a on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.,The purity of-Human Siglec-4a is greater than 95% as determined by SEC-HPLC.
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Myelin Associated Glycoprotein (MAG) (AA 20-516) (Active) protein (Biotin,His-Avi Tag)
MAG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Myelin Associated Glycoprotein (MAG) (AA 1-626) protein (GST tag)MAG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myelin Associated Glycoprotein (MAG) (AA 119-208) protein (GST tag)MAG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myelin Associated Glycoprotein (MAG) protein (Fc Tag,ECD)MAG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Myelin Associated Glycoprotein (MAG) protein (His tag)MAG Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Myelin Associated Glycoprotein (MAG) (AA 20-516) protein (His tag)MAG Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS, 500 mM Nacl ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- MAG (Myelin Associated Glycoprotein (MAG))
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Alternative Name
- Siglec-4a
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Background
- Siglec-4a, also known as Myelin-Associated Glycoprotein (MAG), is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2.
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Molecular Weight
- 81.4 kDa. Due to glycosylation, the protein migrates to 100-115 kDa based on Bis-Tris PAGE result.
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UniProt
- P20916
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Pathways
- Neurotrophin Signaling Pathway
Target
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