MAG Protein (AA 1-626) (GST tag)

Catalog No. ABIN1310019

Product Details

Target: MAG (Myelin Associated Glycoprotein (MAG))

Protein Type: Recombinant

Protein Characteristics: AA 1-626

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This MAG protein is labelled with GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Purpose: MAG (Human) Recombinant Protein (P01)

Sequence: MIFLTALPLF WIMISASRGG HWGAWMPSSI SAFEGTCVSI PCRFDFPDEL RPAVVHGVWY FNSPYPKNYP PVVFKSRTQV VHESFQGRSR LLGDLGLRNC TLLLSNVSPE LGGKYYFRGD LGGYNQYTFS EHSVLDIVNT PNIVVPPEVV AGTEVEVSCM VPDNCPELRP ELSWLGHEGL GEPAVLGRLR EDEGTWVQVS LLHFVPTREA NGHRLGCQAS FPNTTLQFEG YASMDVKYPP VIVEMNSSVE AIEGSHVSLL CGADSNPPPL LTWMRDGTVL REAVAESLLL ELEEVTPAED GVYACLAENA YGQDNRTVGL SVMYAPWKPT VNGTMVAVEG ETVSILCSTQ SNPDPILTIF KEKQILSTVI YESELQLELP AVSPEDDGEY WCVAENQYGQ RATAFNLSVE FAPVLLLESH CAAARDTVQC LCVVKSNPEP SVAFELPSRN VTVNESEREF VYSERSGLVL TSILTLRGQA QAPPRVICTA RNLYGAKSLE LPFQGAHRLM WAKIGPVGAV VAFAILIAIV CYITQTRRKK NVTESPSFSA GDNPPVLFSS DFRISGAPEK YESERRLGSE RRLLGLRGEP PELDLSYSHS DLGKRPTKDS YTLTEELAEY AEIRVK

Characteristics: Human MAG full-length ORF ( NP_002352.1, 1 a.a. - 626 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Miners, Palmer, Love: "Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease." in: Brain pathology (Zurich, Switzerland), (2015) (PubMed).

Barker, Wellington, Esiri, Love: "Assessing white matter ischemic damage in dementia patients by measurement of myelin proteins." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 7, pp. 1050-7, (2013) (PubMed).

Gnanapavan, Grant, Illes-Toth, Lakdawala, Keir, Giovannoni: "Neural cell adhesion molecule--description of a CSF ELISA method and evidence of reduced levels in selected neurological disorders." in: Journal of neuroimmunology, Vol. 225, Issue 1-2, pp. 118-22, (2010) (PubMed).

Target Details

Target: MAG (Myelin Associated Glycoprotein (MAG))

Alternative Name: MAG (MAG Products)

Synonyms: GMA Protein, S-MAG Protein, SIGLEC-4A Protein, SIGLEC4A Protein, siglec-4 Protein, MAG Protein, Gma Protein, siglec-4a Protein, myelin associated glycoprotein Protein, myelin-associated glycoprotein Protein, MAG Protein, mag Protein, Mag Protein

Background: Full Gene Name: myelin associated glycoprotein
Synonyms: GMA,S-MAG,SIGLEC-4A,SIGLEC4A

Gene ID: 4099

NCBI Accession: NM_002361

Pathways: Neurotrophin Signaling Pathway