SIRP-beta Protein (AA 30-369) (His-Avi Tag,Biotin)
SIRPB1A
Origin: Human
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- Target See all SIRP-beta (SIRPB1A) products
- SIRP-beta (SIRPB1A) (Signal-Regulatory Protein beta 1A (SIRPB1A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-369
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIRP-beta protein is labelled with His-Avi Tag,Biotin.
- Purpose
- Biotinylated Human SIRP Beta/CD172b Protein
- Sequence
- Glu30-Ala369
- Characteristics
- Recombinant Biotinylated Human SIRP Beta/CD172b Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Ala369.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Signal-Regulatory Protein beta 1A (SIRPB1A) (AA 30-369) protein (His-Avi Tag)
SIRPB1A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Signal-Regulatory Protein beta 1A (SIRPB1A) (AA 30-371) protein (Fc Tag)SIRPB1A Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SIRP-beta (SIRPB1A) (Signal-Regulatory Protein beta 1A (SIRPB1A))
- Alternative Name
- SIRP Beta (SIRPB1A Products)
- Synonyms
- 9930027N05Rik Protein, SIRP-beta Protein, Sirpb Protein, Sirpb1 Protein, signal-regulatory protein beta 1A Protein, Sirpb1a Protein
- Background
- SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
- Molecular Weight
- 40 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
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