SIRP-beta Protein (AA 30-371) (Fc Tag)

Catalog No. ABIN6253557

Product Details

Target: SIRP-beta (SIRPB1A) (Signal-Regulatory Protein beta 1A (SIRPB1A))

Protein Type: Recombinant

Protein Characteristics: AA 30-371

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SIRP-beta protein is labelled with Fc Tag.

Sequence: AA 30-371

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: SIRP-beta (SIRPB1A) (Signal-Regulatory Protein beta 1A (SIRPB1A))

Alternative Name: SIRP beta (SIRPB1A Products)

Synonyms: 9930027N05Rik Protein, SIRP-beta Protein, Sirpb Protein, Sirpb1 Protein, signal-regulatory protein beta 1A Protein, Sirpb1a Protein

Background: Signal-regulatory protein beta-1 (SIRP beta 1) also known as SIRPβ1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. SIRPβ1 is a transmembrane protein that has three Ig-like domains in its extracellular region and a short cytoplasmic tail. Human SIRPβ1 is expressed on monocytes and granulocytes but not on lymphocytes. SIRP beta 1 contains short cytoplasmic domains that lack cytoplasmic sequence motifs capable of recruiting SHP-2 and SHP-1. In addition, they contain a single basic lysine residue within the hydrophobic transmembrane domain.

Molecular Weight: 63.7 kDa

NCBI Accession: NP_006056