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ULBP2 Protein (AA 26-217) (His-Avi Tag)

Recombinant ULBP2 protein expressed in HEK-293 Cells.
Catalog No. ABIN7275815
$302.18
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Quick Overview for ULBP2 Protein (AA 26-217) (His-Avi Tag) (ABIN7275815)

Target

See all ULBP2 Proteins
ULBP2 (UL16 Binding Protein 2 (ULBP2))

Protein Type

Recombinant

Biological Activity

Active

Origin

Human

Source

  • 8
  • 3
  • 3
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 26-217

    Purification tag / Conjugate

    This ULBP2 protein is labelled with His-Avi Tag.

    Purpose

    Non-biotinylated Human ULBP-2 Protein

    Sequence

    Gly26-Ser217

    Characteristics

    Recombinant Human ULBP-2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly26-Ser217.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human ULBP-2, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 1.96ug/ml determined by ELISA.,Human ULBP-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human ULBP-2 is greater than 95% as determined by SEC-HPLC.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    ULBP2 (UL16 Binding Protein 2 (ULBP2))

    Alternative Name

    ULBP-2

    Background

    ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.

    Molecular Weight

    24.6 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.

    UniProt

    Q9BZM5
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