TENM2 Protein (AA 401-841) (His tag)

Catalog No. ABIN7454217

Recombinant TENM2 protein expressed in HEK-293 Cells.

Quick Overview for TENM2 Protein (AA 401-841) (His tag) (ABIN7454217)

Target: TENM2 (Teneurin Transmembrane Protein 2 (TENM2))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE

Product Details

Protein Characteristics: AA 401-841

Purification tag / Conjugate: This TENM2 protein is labelled with His tag.

Purpose: Human TENM2 Protein

Sequence: Gly401-Asn841

Characteristics: Recombinant Human TENM2 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Gly401-Asn841.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Human TENM2 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, 2 mM DTT ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: TENM2 (Teneurin Transmembrane Protein 2 (TENM2))

Alternative Name: TENM2

Background: Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control.

Molecular Weight: 48.48 kDa. The protein cleaved to 55-65 kDa, 38-43 kDa and 25-30 kDa based on Bis-Tris PAGE result.

UniProt: Q9NT68