TNFRSF10B Protein (AA 53-180) (Fc Tag)
Quick Overview for TNFRSF10B Protein (AA 53-180) (Fc Tag) (ABIN7491067)
Target
See all TNFRSF10B ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 53-180
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Purification tag / Conjugate
- This TNFRSF10B protein is labelled with Fc Tag.
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Purpose
- Recombinant mouse TNFRSF10B protein with C-terminal human Fc tag
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Specificity
- Mouse TNFRSF10B(Asn53-Lys180) hFc(Glu99-Ala330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (Biotin,His-Avi Tag)
TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 53-180) (Active) protein (His tag)TNFRSF10B Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (His-Avi Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (hFc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) protein (mFc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-180) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (Fc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Active) proteinTNFRSF10B Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 52-183) protein (His-IF2DI Tag)TNFRSF10B Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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Alternative Name
- TNFRSF10B
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Background
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Death receptor 5,MK,CD262
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. -
Molecular Weight
- predicted molecular mass of 40.3 kDa after removal of the signal peptide. The apparent molecular mass of mTNFRSF10B-hFc is 40-55 kDa due to glycosylation.
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UniProt
- Q9QZM4
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Pathways
- p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
Target
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