Quick Overview for CCL1 Protein (ABIN7455623)
Target
See all CCL1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed.
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Characteristics
- Extracellular Domain Protein
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Purification
- Affinity purification
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Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-96) (Active) protein (His tag)
CCL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 1-96) protein (GST tag)CCL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-96) protein (His tag)CCL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))
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Alternative Name
- CCL1
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Background
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C-C Motif Chemokine 1,Small-Inducible Cytokine A1,T Lymphocyte-Secreted Protein I-309,CCL1,SCYA1
Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42 % amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection. -
Molecular Weight
- 8.62 KDa
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UniProt
- P22362
Target
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