Thyroperoxidase Protein (His tag)
Quick Overview for Thyroperoxidase Protein (His tag) (ABIN7455633)
Target
See all Thyroperoxidase (TPO) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Thyroperoxidase protein is labelled with His tag.
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Purpose
- Recombinant Human Thrombopoietin is produced by our Mammalian expression system and the target gene encoding Ser22-Gly353 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Thyroid Peroxidase (TPO) (AA 32-834) (Active) protein (His tag)
TPO Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Thyroid Peroxidase (TPO) (AA 19-846) (Active) protein (His tag)TPO Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Thyroid Peroxidase (TPO) (AA 672-779) protein (GST tag)TPO Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Thyroid Peroxidase (TPO) (AA 1-933) protein (GST tag)TPO Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Thyroid Peroxidase (TPO) (Active) protein (His tag)GMP Grade TPO Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % WB Active
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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Alternative Name
- TPO
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Background
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Thrombopoietin,C-mpl ligand,Megakaryocyte colony-stimulating factor,Megakaryocyte growth and development factor,Myeloproliferative leukemia virus oncogene ligand,THPO
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. -
Molecular Weight
- 37.3 KDa
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UniProt
- P40225
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Pathways
- Thyroid Hormone Synthesis
Target
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