ELAPOR1 Protein (His tag)

Catalog No. ABIN7455652

This Recombinant ELAPOR1 protein is produced in HEK-293 Cells.

Quick Overview for ELAPOR1 Protein (His tag) (ABIN7455652)

Target: ELAPOR1 (Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 (ELAPOR1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: Greater than 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This ELAPOR1 protein is labelled with His tag.

Purpose: Recombinant Human Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 is produced by our Mammalian expression system and the target gene encoding Thr42-Lys910 is expressed with a 6His tag at the C-terminus.

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: ELAPOR1 (Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 (ELAPOR1))

Alternative Name: ELAPOR1

Background: ELAPOR1,ndosome-Lysosome Associated Apoptosis And Autophagy Regulator 1,IG121,IAA1324
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated with breast and endometrial cancers,but its mechanism of action remains unknown.May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. That EIG121 is a good endometrial biomarker associated with a hyperestrogenic state and estrogen-related type I endometrial adenocarcinoma.

Molecular Weight: 96.2 KDa

UniProt: Q6UXG2