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IL29 Protein (His tag)

This Recombinant IL29 protein is produced in HEK-293 Cells.
Catalog No. ABIN7455655

Quick Overview for IL29 Protein (His tag) (ABIN7455655)

Target

See all IL29 Proteins
IL29 (Interleukin 29 (IL29))

Protein Type

Recombinant

Origin

  • 16
  • 1
Human

Source

  • 9
  • 4
  • 2
  • 1
HEK-293 Cells

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Purification tag / Conjugate

    This IL29 protein is labelled with His tag.

    Purpose

    Recombinant Human Interferon Lambda-1 is produced by our Mammalian expression system and the target gene encoding Gly20-Thr200 is expressed with a 10His tag at the C-terminus.

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    IL29 (Interleukin 29 (IL29))

    Alternative Name

    IL-29

    Background

    Interleukin-29 (IL-29) is a secreted protein which belongs to the IL-28/IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10R beta) and an orphan class II receptor chain, designated IL-28R alpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

    Molecular Weight

    21.4 KDa

    UniProt

    Q8IU54
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