CCL16 Protein
-
- Target See all CCL16 Proteins
- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
- Protein Type
- Recombinant
- Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human C-C Motif Chemokine 16 is produced by our E.coli expression system and the target gene encoding Gln24-Gln120 is expressed.
- Characteristics
- Extracellular Domain Protein
- Top Product
- Discover our top product CCL16 Protein
-
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)
CCL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 25-120) protein (GST tag)CCL16 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)Crystallography grade CCL16 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)CCL16 Origin: Human Host: Yeast (Pichia pastoris) Recombinant > 95 % SDS, WB, ELISA, IP
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
- Alternative Name
- CCL16 (CCL16 Products)
- Synonyms
- CKb12 Protein, HCC-4 Protein, ILINCK Protein, LCC-1 Protein, LEC Protein, LMC Protein, Mtn-1 Protein, NCC-4 Protein, NCC4 Protein, SCYA16 Protein, SCYL4 Protein, C-C motif chemokine ligand 16 Protein, CCL16 Protein, Ccl16 Protein
- Background
- C-C Motif Chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-Inducible Chemokine, LCC-1, Liver-Expressed Chemokine, Lymphocyte and Monocyte Chemoattractant, LMC, Monotactin-1, MTN-1, NCC-4, Small-Inducible Cytokine A16, CCL16, ILINCK, NCC4, SCYA16CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30 % sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
- Molecular Weight
- 11 KDa
- UniProt
- O15467
-
