ENTPD2 Protein (His tag)

Catalog No. ABIN7489091

Recombinant ENTPD2 protein expressed in CHO Cells.

Quick Overview for ENTPD2 Protein (His tag) (ABIN7489091)

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: CHO Cells

Purity: 95 %

Grade: MALS verified

Product Details

Purification tag / Conjugate: This ENTPD2 protein is labelled with His tag.

Purpose: Human CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)

Sequence: Thr 29 - Asp 460

Characteristics: Human CD39L1/ENTPD2 Protein, His Tag is expressed from CHO cells. It contains AA Thr 29 - Asp 460 (Accession # Q9Y5L3-1).

Endotoxin Level: 1.0 EU per μg

Application Details

Comment:

This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 49.0 kDa. The protein migrates as 36-37 kDa and 57-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris, 150 mM NaCl, pH 7.5

Storage: -80 °C

Storage Comment: -70°C

Target Details

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Alternative Name: CD39L1

Background: CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.

Molecular Weight: 49.0 kDa