CXCR3 Protein-VLP
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- Target See all CXCR3 Proteins
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
- Protein Type
- VLP
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CXCR3 Full Length Protein (VLP)
- Sequence
- Val 2 - Leu 368
- Characteristics
- Human CXCR3 Full Length Protein-VLP is expressed from human 293 cells (HEK293). It contains AA Val 2 - Leu 368 (Accession # P49682-1).
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product CXCR3 Protein
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Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 121-220) protein (GST tag)
CXCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-53) protein (GST tag)CXCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) protein (GST tag)CXCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) protein (Fc Tag)CXCR3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, Arginine, pH 7.4
- Storage
- -80 °C
- Storage Comment
- -70°C
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- Target
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
- Alternative Name
- CXCR3 (CXCR3 Products)
- Synonyms
- CD182 Protein, CD183 Protein, CKR-L2 Protein, CMKAR3 Protein, GPR9 Protein, IP10-R Protein, Mig-R Protein, MigR Protein, Cd183 Protein, Cmkar3 Protein, CXCR3 Protein, cxcr3 Protein, Gpr9 Protein, CXC-R3 Protein, CXCR-3 Protein, zgc:92301 Protein, sb:eu378 Protein, C-X-C motif chemokine receptor 3 Protein, chemokine (C-X-C motif) receptor 3 Protein, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 Protein, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 Protein, CXCR3 Protein, Cxcr3 Protein, cxcr3 Protein, cxcr3.2 Protein, cxcr3.1 Protein
- Background
- Chemokines are proteins which induce chemotaxis, promote differentiation of immune cells, and cause tissue extravasation. Given these properties, their role in anti-tumor immune response in the cancer environment is of great interest. Although immunotherapy has shown clinical benefit for some cancer patients, other patients do not respond. One of the mechanisms of resistance to checkpoint inhibitors may be chemokine signaling. The CXCL9, -10, -11/CXCR3 axis regulates immune cell migration, differentiation, and activation, leading to tumor suppression (paracrine axis). However, there are some reports that show involvements of this axis in tumor growth and metastasis (autocrine axis). Thus, a better understanding of CXCL9, -10, -11/CXCR3 axis is necessary to develop effective cancer control.
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