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IL-2 Protein (AA 21-153)

This Recombinant IL-2 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7504444

Quick Overview for IL-2 Protein (AA 21-153) (ABIN7504444)

Target

See all IL-2 (IL2) Proteins
IL-2 (IL2) (Interleukin 2 (IL2))

Protein Type

Recombinant

Origin

  • 46
  • 26
  • 9
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
Human

Source

  • 50
  • 28
  • 23
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 21-153

    Purpose

    Human IL-2 Protein

    Sequence

    Ala21-Thr153

    Characteristics

    Recombinant Human IL-2 Protein is expressed from HEK293 without tag.It contains Ala21-Thr153.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 0.05 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    IL-2 (IL2) (Interleukin 2 (IL2))

    Alternative Name

    IL-2

    Background

    Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells.

    Molecular Weight

    15.41 kDa same as Tris-Bis PAGE result.

    UniProt

    P60568

    Pathways

    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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