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IL-2 Protein (AA 21-153)

IL2 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018088
  • Target See all IL-2 (IL2) Proteins
    IL-2 (IL2) (Interleukin 2 (IL2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 21-153
    Origin
    • 28
    • 16
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 41
    • 25
    • 19
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    CHO Cells
    Characteristics
    ED50 < 2 ng/mL, measured in a cell proliferation assay using CTLL-2 cells.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product IL2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS..
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    IL-2 (IL2) (Interleukin 2 (IL2))
    Alternative Name
    Interleukin-2 (IL-2) (IL2 Products)
    Synonyms
    IL2 Protein, IL-2 Protein, il2 Protein, TCGF Protein, lymphokine Protein, Il-2 Protein, POIL2 Protein, interleukin 2 Protein, interleukin-15 Protein, IL2 Protein, il2 Protein, LOC100303688 Protein, Il2 Protein
    Background
    Interleukin-2 (IL-2) is a Oglycosylated, four alpha-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, gamma delta T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
    Synonyms: T-cell growth factor (TCGF), Aldesleukin
    Molecular Weight
    15-16 kDa, observed by reducing SDS-PAGE.
    UniProt
    P60568
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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