Transferrin Receptor Protein (AA 89-763) (His tag)

Catalog No. ABIN7504555

This Recombinant Transferrin Receptor protein is expressed in HEK-293 Cells.

Quick Overview for Transferrin Receptor Protein (AA 89-763) (His tag) (ABIN7504555)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 89-763

Purification tag / Conjugate: This Transferrin Receptor protein is labelled with His tag.

Purpose: Mouse Transferrin R/CD71 Protein

Sequence: Cys89-Phe763

Characteristics: Recombinant Mouse Transferrin R/CD71 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Cys89-Phe763.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, 200 mM L-arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: Transferrin R

Background: The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.

Molecular Weight: 76.99 kDa. Due to glycosylation, the protein migrates to 78-90 kDa based on Tris-Bis PAGE result.

UniProt: Q62351

Pathways: Transition Metal Ion Homeostasis