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SQSTM1 Protein (AA 3-102) (His tag)

SQSTM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505152
  • Target See all SQSTM1 Proteins
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 3-102
    Origin
    • 8
    • 2
    • 1
    • 1
    Human
    Source
    • 8
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SQSTM1 protein is labelled with His tag.
    Sequence
    Ser 3-Lys 102
    Characteristics
    A DNA sequence encoding the Human SQSTM1 protein (Q13501) (Ser 3-Lys 102) was expressed with a N-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Alternative Name
    SQSTM1 (SQSTM1 Products)
    Background

    Abbreviation: SQSTM1,p62

    Target Synonym: A170,DMRV,EBI 3 associated protein p60,EBIAP,FTDALS3,ORCA,OSF-6,OSIL,p60,P62b,PDB 3,PDB3,Sequestosome 1,SQSTM 1,STAP,STONE14,ZIP3

    Background: Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

    Molecular Weight

    Calculated MW: 10.89 kDa

    Observed MW: 15 kDa

    UniProt
    Q13501
    Pathways
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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