SQSTM1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all SQSTM1 Proteins
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SQSTM1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SQSTM1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SQSTM1 Protein
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Sequestosome 1 (SQSTM1) (AA 108-237) protein (His-IF2DI Tag)
SQSTM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Sequestosome 1 (SQSTM1) (AA 85-440) protein (His tag)SQSTM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Sequestosome 1 (SQSTM1) (AA 1-356) protein (His tag)SQSTM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS-PAGE SDS
Sequestosome 1 (SQSTM1) (AA 1-440) protein (GST tag)SQSTM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sequestosome 1 (SQSTM1) (AA 2-440) protein (His tag)Crystallography grade SQSTM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sequestosome 1 (SQSTM1) (AA 2-442) protein (His tag)Crystallography grade SQSTM1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Alternative Name
- Sqstm1 (SQSTM1 Products)
- Synonyms
- SQSTM1 Protein, sqstm1 Protein, MGC79491 Protein, A170 Protein, OSIL Protein, PDB3 Protein, ZIP3 Protein, p60 Protein, p62 Protein, p62B Protein, OSF-6 Protein, Osi Protein, STAP Protein, ZIP Protein, sb:cb621 Protein, zgc:85784 Protein, sequestosome 1 Protein, sequestosome 1 L homeolog Protein, SQSTM1 Protein, sqstm1 Protein, Sqstm1 Protein, sqstm1.L Protein
- Background
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
- Molecular Weight
- 47.5 kDa
- NCBI Accession
- NP_003891
- Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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