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Hepcidin Protein (AA 59-83) (TRX tag,His tag)

This Recombinant Hepcidin protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7505380
$229.92
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Quick Overview for Hepcidin Protein (AA 59-83) (TRX tag,His tag) (ABIN7505380)

Target

See all Hepcidin (HAMP) Proteins
Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Protein Type

Recombinant

Origin

  • 10
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Mouse

Source

  • 16
  • 3
  • 3
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 59-83

    Purification tag / Conjugate

    This Hepcidin protein is labelled with TRX tag,His tag.

    Sequence

    Asp59-Thr83

    Characteristics

    A DNA sequence encoding the Mouse Hepc protein (Q9EQ21) (Asp59-Thr83) was expressed with a N terminal His-TRX tag.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

    Alternative Name

    Hepcidin

    Background

    Abbreviation: Hepcidin,Hepc

    Target Synonym: Hepcidin,HEPC_MOUSE,Hamp,Hamp1,Hepc,Hepc1

    Background: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.

    Molecular Weight

    Calculated MW: 22.64 kDa

    Observed MW: 25 kDa

    UniProt

    Q9EQ21

    Pathways

    Hormone Activity, Transition Metal Ion Homeostasis
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