ALPL Protein (AA 18-501) (His tag)
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- Target See all ALPL Proteins
- ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 18-501
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ALPL protein is labelled with His tag.
- Sequence
- Phe 18-Gly 501
- Characteristics
- A DNA sequence encoding the Mouse ALPL protein (P09242) (Phe 18-Gly 501) was expressed with a N-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ALPL Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
- Alternative Name
- ALPL (ALPL Products)
- Synonyms
- ALP Protein, iap Protein, alpl Protein, AP-TNAP Protein, APTNAP Protein, HOPS Protein, TNAP Protein, TNSALP Protein, Akp-2 Protein, Akp2 Protein, PHOA Protein, TNS-AP Protein, alkaline phosphatase, liver/bone/kidney L homeolog Protein, alkaline phosphatase, liver/bone/kidney Protein, alkaline phosphatase, intestinal, gene 2 Protein, alkaline phosphatase, liver/bone/kidney pseudogene Protein, alpl.L Protein, ALPL Protein, alpi.2 Protein, LOC100031702 Protein, Alpl Protein
- Background
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Abbreviation: ALPL
Target Synonym: AP-TNAP,TNAP,TNSALP,Alkaline phosphatase 2,Alkaline phosphatase liver/bone/kidney isozyme,Phosphoamidase,Phosphocreatine phosphatase
Background: Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. Alkaline phosphatases (APs) are ubiquitous in many species, from bacteria to human. Four genes encode AP isoenzymes in humans and rodents. Three AP genes are expressed in a tissue-specific manner (i.e., placental, embryonic, and intestinal AP isoenzymes). Expression of the fourth AP gene is nonspecific to a single tissue and is especially abundant in bone, liver, and kidney. This isoenzyme is also called tissue-nonspecific alkaline phosphatase (TNAP). The enzyme tissue non-specific alkaline phosphatase (TNAP) belongs to the ectophosphatase family. TNAP is present in large amounts in bone in which it plays a role in mineralization.
- Molecular Weight
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Calculated MW: 53.13 kDa
Observed MW: 58 kDa
- UniProt
- P09242
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