VEGF Protein (AA 27-190) (His tag)

Catalog No. ABIN7505468

This Recombinant VEGF protein is expressed in Escherichia coli (E. coli).

Quick Overview for VEGF Protein (AA 27-190) (His tag) (ABIN7505468)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Protein Type: Recombinant

Origin: Pig

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 27-190

Purification tag / Conjugate: This VEGF protein is labelled with His tag.

Sequence: Ala 27-Arg 190

Characteristics: A DNA sequence encoding the Porcine VEGF/VEGFA protein (P49151) (Ala 27-Arg 190) was expressed with N-His tag.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Alternative Name: VEGF

Background:

Abbreviation: Porcine VEGF,VEGFA

Target Synonym: VEGF-A

Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Molecular Weight:

Calculated MW: 17.93 kDa

Observed MW: 20 kDa

UniProt: P49151