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VEGF Protein (Vascular Endothelial Growth Factor) (AA 27-190)

HPLC verified VEGF Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN2181901
$469.23
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  • Target See all VEGF Proteins
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 27-190
    Origin
    • 15
    • 8
    • 2
    Mouse
    Source
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Brand
    ActiveMax®
    Sequence
    AA 27-190
    Characteristics
    This protein carries no "tag". The protein has a calculated MW of 19.3 kDa. The protein migrates as 23-25 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Grade
    HPLC verified
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    Alternative Name
    VEGF (VEGF Products)
    Synonyms
    MVCD1, VEGF, VPF, Vegf, Vegf120, Vegf164, Vegf188, Vpf, VEGF-A, VEGF164, eVEGF120, eVEGF164, vegf-a, vegf, vascular endothelial growth factor A, vascular endothelial growth factor A L homeolog, vascular endothelial growth factor, vascular endothelial growth factor precursor, VEGFA, Vegfa, vegfa.L, VEGF, vegf
    Background
    Vascular endothelial growth factor A (VEGFA) is also known as Vascular permeability factor (VPF). VEGFA belongs to the PDGF/VEGF growth factor family. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. VEGFA is produced by a group of three major isoforms as a result of alternative splicing and if any three isoforms are produced (VEGFA120, VEGFA164, and VEGFA188) then this will not result in vessel defects and death of the full VEGFA knockout in mice.
    Molecular Weight
    19.3 kDa
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