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Adipsin Protein (AA 1-259) (His tag)

CFD Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505743
  • Target See all Adipsin (CFD) Proteins
    Adipsin (CFD) (Complement Factor D (CFD))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-259
    Origin
    • 14
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 10
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Adipsin protein is labelled with His tag.
    Sequence
    Met1-Ser259
    Characteristics
    A DNA sequence encoding the Mouse Cfd protein (P03953) (1-259) was expressed with a C-His.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    Adipsin (CFD) (Complement Factor D (CFD))
    Alternative Name
    Complement Factor D (CFD Products)
    Background

    Abbreviation: Factor D,Cfd

    Target Synonym: Complement factor D,28 kDa adipocyte protein,Adipsin,C3 convertase activator,Properdin factor D,Cfd,Adn,Df

    Background: Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.

    Molecular Weight

    Calculated MW: 28.38 kDa

    Observed MW: 40 kDa

    UniProt
    P03953
    Pathways
    Complement System
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