CCL13 Protein
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- Target See all CCL13 Proteins
- CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Yeast (Pichia pastoris)
- Purpose
- Recombinant Human CCL13/MCP-4 Protein
- Sequence
- QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
- Specificity
- Gln24-Thr98
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Top Product
- Discover our top product CCL13 Protein
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Chemokine (C-C Motif) Ligand 13 (CCL13) (Active) protein
CCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 24-98) protein (His tag)CCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 1-98) protein (GST tag)CCL13 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 17-98) protein (His tag)Crystallography grade CCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 22-98) protein (His tag)Crystallography grade CCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 17-98) protein (His tag)CCL13 Origin: Human Host: Yeast (Pichia pastoris) Recombinant > 95 % SDS, WB, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
- Alternative Name
- CCL13/MCP-4 (CCL13 Products)
- Synonyms
- CKb10 Protein, MCP-4 Protein, NCC-1 Protein, NCC1 Protein, SCYA13 Protein, SCYL1 Protein, C-C motif chemokine ligand 13 Protein, chemokine (C-C motif) ligand 13 Protein, CCL13 Protein
- Background
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Description: Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chemokines, CCL13 binds to several chemokine receptors (CCR1, CCR2 and CCR3), allowing it to elicit different effects on its target cells. A number of studies have shown that CCL13 is involved in many chronic inflammatory diseases, in which it functions as a pivotal molecule involved in the selective recruitment of cell lineages to the inflamed tissues and their subsequent activation. MCP-4/CCL13 is secreted from chondrocytes and activates the proliferation of rheumatoid synovial cells, thereby leading to joint destruction in RA.
Name: CCL13,CKb10,MCP-4,NCC-1,NCC1,SCYA13,SCYL1
- Gene ID
- 6357
- UniProt
- Q99616
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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