CCL21 Protein
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- Target See all CCL21 Proteins
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human CCL21 Protein
- Sequence
- SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P
- Specificity
- Ser24-Pro134
- Purity
- > 85 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Top Product
- Discover our top product CCL21 Protein
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Chemokine (C-C Motif) Ligand 21 (CCL21) (Active) protein
CCL21 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 21 (CCL21) (AA 24-133) protein (His tag)CCL21 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 21 (CCL21) (AA 1-134) protein (GST tag)CCL21 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 21 (CCL21) (AA 24-134) protein (His tag)Crystallography grade CCL21 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.58 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Alternative Name
- CCL21 (CCL21 Products)
- Synonyms
- 6Ckine Protein, CKb9 Protein, ECL Protein, SCYA21 Protein, SLC Protein, TCA4 Protein, ccl21 Protein, Ccl21b Protein, C-C motif chemokine ligand 21 Protein, C-C motif chemokine 21 Protein, CCL21 Protein, ccl21 Protein, Ccl21 Protein
- Background
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Description: Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 21(CCL21), also known as 6Ckine, exodus-2, and secondary lymphoid-tissue chemokine(SLC), is a small cytokine belonging to the C-C chemokine family. CCL21 takes its name 6Ckine for its consititutively six conserved cysteine residues but not four cysteines typical to chemokines. CCL21 has function in ininducing vigorous calcium migrations and chemotactic responses.
Name: CCL21,6Ckine,CKb9,ECL,SCYA21,SLC,TCA4
- Gene ID
- 6366
- UniProt
- O00585
- Pathways
- Regulation of Actin Filament Polymerization
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