IFNA2 Protein

Catalog No. ABIN7536338

This Recombinant IFNA2 protein is produced in Yeast (Pichia pastoris).

Quick Overview for IFNA2 Protein (ABIN7536338)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Protein Type: Recombinant

Origin: Mouse

Source: Yeast (Pichia pastoris)

Product Details

Purpose: Recombinant Mouse IFN-alpha 2 Protein

Sequence: CDLPHTYNLR NKRALKVLAQ MRRLPFLSCL KDRQDFGFPL EKVDNQQIQK AQAIPVLRDL TQQTLNLFTS KASSAAWNAT LLDSFCNDLH QQLNDLQTCL MQQVGVQEPP LTQEDALLAV RKYFHRITVY LREKKHSPCA WEVVRAEVWR ALSSSVNLLP RLSEEKE

Specificity: Cys24-Glu190

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.1EU/μg

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 0.62 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Alternative Name: IFN-alpha 2

Background:

Description: IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.

Name: IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon alpha-2,Interferon alpha 2 (IFN-α2),IFN-alphaA,IFNA,IFNA2B,INFA2

Gene ID: 15965

UniProt: P01573

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C