s100a4 Protein
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- Target See all s100a4 (S100A4) Proteins
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human S100-A4 Protein
- Sequence
- ACPLEKALDV MVSTFHKYSG KEGDKFKLNK SELKELLTRE LPSFLGKRTD EAAFQKLMSN LDSNRDNEVD FQEYCVFLSC IAMMCNEFFE GFPDKQPRKK
- Specificity
- Ala2-Lys101
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Top Product
- Discover our top product S100A4 Protein
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S100 Calcium Binding Protein A4 (S100A4) (AA 1-101) protein (GST tag)
S100A4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
S100 Calcium Binding Protein A4 (S100A4) (Active) proteinS100A4 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
S100 Calcium Binding Protein A4 (S100A4) protein (His tag)S100A4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
S100 Calcium Binding Protein A4 (S100A4) protein (Fc Tag)S100A4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
S100 Calcium Binding Protein A4 (S100A4) (AA 2-101) protein (His tag)Crystallography grade S100A4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
- Alternative Name
- S100-A4 (S100A4 Products)
- Synonyms
- 18A2 Protein, 42A Protein, CAPL Protein, FSP1 Protein, MTS1 Protein, P9KA Protein, PEL98 Protein, 42a Protein, Capl Protein, FSp1 Protein, Mts1 Protein, PeL98 Protein, metastasin Protein, pk9a Protein, S100A4 Protein, P9ka Protein, RNP9KA Protein, S100 calcium binding protein A4 Protein, S100 calcium-binding protein A4 Protein, S100A4 Protein, S100a4 Protein
- Background
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Description: S100A4 belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is necessary for S100A4 to interact with its protein targets and generate biological effects. It can bind the already known targets p53, F-actin, liprin β, myosin heavy chain II, and prevent their phosphorylation and multimerization. It has been demonstrated that S100A4 is directly involved in tumor metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation, and appears to be a metastasis factor and a molecular marker for clinical prognosis. Multiple alternatively spliced variants encoding the same protein have been identified.
Name: 18A2,42A,CAPL,FSP1,MTS1,P9KA,PEL98,S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, protein S100-A4
- Gene ID
- 6275
- UniProt
- P26447
- Pathways
- S100 Proteins
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