BAMBI Protein (AA 27-152) (Fc Tag)
Quick Overview for BAMBI Protein (AA 27-152) (Fc Tag) (ABIN7852614)
Target
See all BAMBI ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 27-152
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Purification tag / Conjugate
- This BAMBI protein is labelled with Fc Tag.
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Purpose
- Recombinant human BAMBI Protein with C-terminal human Fc tag
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Specificity
- BAMBI (Glu27-Ala152) hFc (Glu99-Ala330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
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Alternative Name
- BAMBI
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Background
- This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]
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Molecular Weight
- predicted molecular mass of 40.1 kDa after removal of the signal peptide. The apparent molecular mass of BAMBI-hFc is 55-70 kDa due to glycosylation.
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UniProt
- Q13145
Target
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