FGF10 Protein

Catalog No. ABIN7539320

This Recombinant FGF10 protein is expressed in Escherichia coli (E. coli).

Quick Overview for FGF10 Protein (ABIN7539320)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % by SDS-PAGE

Product Details

Purpose: FGF-10

Sequence: MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS

Specificity: Chromosomal location:5p13-p12

Cross-Reactivity: Chicken, Human, Mouse

Characteristics: Length (aa):170

Application Details

Application Notes: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/mL, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: The lyophilized FGF-10 should be reconstituted in water to a concentration not lower than 50 μg/mL. For long term storage we would recommend to add at least 0.1 % human or bovine serum albumin.

Buffer: 0.5X PBS

Storage: -20 °C,-80 °C

Storage Comment: Lyophilized samples are stable for more than six months at -20°C to -70°C.

Target Details

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Alternative Name: FGF-10

Background: FGF10, KGF2,Fibroblast Growth Factor-10 (FGF-10) is a heparin binding growth factor which stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is most related to KGF/FGF-7 and is expressed during development and preferentially in adult lungs. Human FGF-10 is a 19.3 kDa protein containing 170 amino acid residues.

Molecular Weight: 19.3 kDa

Gene ID: 2255

NCBI Accession: NM_004465, NP_004456

UniProt: O15520

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus