C1orf128 Protein (AA 1-211) (His tag)

Catalog No. ABIN7550716

This Recombinant C1orf128 protein is produced in HEK-293 Cells.

Quick Overview for C1orf128 Protein (AA 1-211) (His tag) (ABIN7550716)

Target: C1orf128 (PITHD1) (PITH (C-Terminal Proteasome-Interacting Domain of Thioredoxin-Like) Domain Containing 1 (PITHD1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-211

Purification tag / Conjugate: This C1orf128 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant PITHD1 Protein expressed in mammalian cells.

Sequence: MSHGHSHGGG GCRCAAEREE PPEQRGLAYG LYLRIDLERL QCLNESREGS GRGVFKPWEE RTDRSKFVES DADEELLFNI PFTGNVKLKG IIIMGEDDDS HPSEMRLYKN IPQMSFDDTE REPDQTFSLN RDLTGELEYA TKISRFSNVY HLSIHISKNF GADTTKVFYI GLRGEWTELR RHEVTICNYE ASANPADHRV HQVTPQTHFI S Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: C1orf128 (PITHD1) (PITH (C-Terminal Proteasome-Interacting Domain of Thioredoxin-Like) Domain Containing 1 (PITHD1))

Alternative Name: PITHD1

Background: PITH domain-containing protein 1,FUNCTION: Promotes megakaryocyte differentiation by up-regulating RUNX1 expression (PubMed:25134913). Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (PubMed:25134913). {ECO:0000269|PubMed:25134913}.

Molecular Weight: 24.2 kDa

UniProt: Q9GZP4

AlphaFold: Q9GZP4