ZNF658 Protein (AA 1-1059) (His tag)

Catalog No. ABIN7556157

Recombinant ZNF658 protein expressed in HEK-293 Cells.

Quick Overview for ZNF658 Protein (AA 1-1059) (His tag) (ABIN7556157)

Target: ZNF658 (Zinc Finger Protein 658 (ZNF658))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-1059

Purification tag / Conjugate: This ZNF658 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant ZNF658 Protein expressed in mammalian cells.

Sequence: MNMSQASVSF QDVTVEFTRE EWQHLGPVER TLYRDVMLEN YSHLISVGYC ITKPKVISKL EKGEEPWSLE DEFLNQRYPG YFKVDHIKGI REKQEKPLWQ EIFISDADKT LSKEGQKVLE KPFNLEIAPE LSEKISCKCD SHRMNLPVAS QLIISERKYS RKKTEYMNVC EKLQLDIKHE KAHAEEKSYE HGENAKAFSY KKDQHWKFQT LEESFECDGS GQGLYDKTIC ITPQSFLTGE KSCKDDEFRK NFDKITLFNH MRTDTRGKCS DLNEYGTSCD KTTAVEYNKV HMAMTHYECN ERGINFSRKS PLTQSQRTIT GWSAFESNKC EENFSQSSAH IVHQKTQAGD KFGEHNECTD ALYQKLDFTA HQRIHTEDKF YLSDEHGKCR KSFYRKAHLI QHQRPHSGEK TYQYEECAKS FCSSSHPIQH PGTYVGFKLY ECNECGKAFC QNSNLSKHLR IHTKEKPCDN NGCGRSYKSP LIGHQKTDAE MELCGGSEYG KTSHLKGHQR ILMGEKPYEC IECGKTFSKT SHLRAHQRIH TGEKPYECVE CEKTFSHKTH LSVHQRVHTG EKPYECNDCG KSFTYNSALR AHQRIHTGEK PYECSDCEKT FAHNSALRAH HRIHTGEKPY ECNECGRSFA HISVLKAHQR IHTGEKPYEC NECGRSFTYN SALRAHQRIH TGRKPYECSD CEKTFAHNSA LKIHQRIHTG EKPYECNECE KTFAHNSALR AHQNIHTGEK LYECSECGKT FFQKTRLSTH RRIHTGEKPY ECSKCGKTFS QKSYLSGHER IHTGEKPYEC NVCGKTFVYK AALIVHQRIH TGEKPYECNQ CGKTFSQRTH LCAHQRIHTG EKPYECNECG KTFADNSALR AHHRIHTGEK PYECNDCGKT FSKTSHLRAH LRTRSGEKPY ECSECGKTFS EKSYVSAHQR VHTGEKPYEC NVCGKPFAHN STLRVHQRIH TGEKSYECND CGKTFSQKSH LSAHQRIHTG EKPYECNECG KAFAQNSTLR VHQRIHTGEK PYECDECGKT FVRKAALRVH HTRMHTREKT LACNGFGKS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ZNF658 (Zinc Finger Protein 658 (ZNF658))

Alternative Name: ZNF658

Background: Zinc finger protein 658,FUNCTION: Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply. {ECO:0000269|PubMed:25582195}.

Molecular Weight: 122.3 kDa

UniProt: Q5TYW1

AlphaFold: Q5TYW1