RPL10L Protein (AA 1-214) (His tag)

Catalog No. ABIN7556766

Recombinant RPL10L protein expressed in HEK-293 Cells.

Quick Overview for RPL10L Protein (AA 1-214) (His tag) (ABIN7556766)

Target: RPL10L (Ribosomal Protein L10L (RPL10L))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-214

Purification tag / Conjugate: This RPL10L protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Rpl10l Protein expressed in mammalian cells.

Sequence: MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVIE ALRRAKFKFP GRQKIHISKK WGFTKFNADE FEDKVAAKRL IPDGCGVKYI PERGPLDKWR ALHS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: RPL10L (Ribosomal Protein L10L (RPL10L))

Alternative Name: Rpl10l

Background: Large ribosomal subunit protein uL16-like (60S ribosomal protein L10-like),FUNCTION: Testis-specific component of the ribosome, which is required for the transition from prophase to metaphase in male meiosis I (PubMed:28502657). Compensates for the inactivated X-linked RPL10 paralog during spermatogenesis (PubMed:28502657). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:28502657). The male germ cell-specific ribosome displays a ribosomal polypeptide exit tunnel of distinct size and charge states compared with the classical ribosome (PubMed:36517592). It is responsible for regulating the biosynthesis and folding of a subset of male germ-cell-specific proteins that are essential for the formation of sperm (PubMed:36517592). {ECO:0000269|PubMed:28502657, ECO:0000269|PubMed:36517592}.

Molecular Weight: 24.6 kDa

UniProt: P86048

AlphaFold: P86048