CYP2D11 Protein (AA 1-504) (His tag)

Catalog No. ABIN7562997

Recombinant CYP2D11 protein expressed in HEK-293 Cells.

Quick Overview for CYP2D11 Protein (AA 1-504) (His tag) (ABIN7562997)

Target: CYP2D11 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 11 (CYP2D11))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-504

Purification tag / Conjugate: This CYP2D11 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Cyp2d11 Protein expressed in mammalian cells.

Sequence: MELLTGAGLW SVAIFTVIFI LLVDLMHRHQ HWTSRCPPGP VPWPVLGNLL QVDLGNMPYS LYKLQNRYGD VFSLQMGWKP MVVINGLKAM KEVLLTCGED TADRPQVPIF EYLGVKPGSQ GVVLAPYGPE WQEQRRFSVS TLRNFGLGKK SLEDWVTKEA RHLCDAFTAQ AGQSINPNTM LNNAVCNVIA SLIFARRFEY EDPYLIRMLK MLKECFTEIS GFIPGVLNEF PIFLRIPGLA DMVFQGQKSF MAILDNLLTE NRTTWDPDQP PRNLTDAFLA EIEKAKGNPE SSFNDENLRM VVGDLFTAGM VTTSTTLSWA LLLMILHPDV QRRVQQEIDA VIGQVQHPEM ADQARMPYTN AVIHEVQRFG DIAPLPLPRI TSRDIEVQDF LVTKGSTLIP NMSSVLKDET VWEKPLRFHP EHFLDAQGHF VKPEAFMPFS AGHRSCLGEA LARMELFLFF TCLLQRFSIS VPDGQPQPSN YRVHAIPVAP FPYQLCAVMR EQGH Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CYP2D11 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 11 (CYP2D11))

Alternative Name: Cyp2d11

Background: Cytochrome P450 2D11 (EC 1.14.14.1) (CYPIID11) (Cytochrome P450-16-alpha) (Cytochrome P450CC) (Testosterone 16-alpha hydroxylase),FUNCTION: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Molecular Weight: 57.0 kDa

UniProt: P24457

AlphaFold: P24457