TTC7A Protein (AA 1-858) (His tag)

Catalog No. ABIN7564335

Recombinant TTC7A protein expressed in HEK-293 Cells.

Quick Overview for TTC7A Protein (AA 1-858) (His tag) (ABIN7564335)

Target: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-858

Purification tag / Conjugate: This TTC7A protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Ttc7a Protein expressed in mammalian cells.

Sequence: MAAKGAHGTH LKVESEVERC RAEGQWDRMF ELARHLQMLG ISGGGSSNRR NSPSGRFTTL DTDDFVKLLL AEALLEQCLK DNHDKIKNSI PLLEKTDHRL NEAKDHLSSL LNNGKLPPQY MCEAMLILGK LHYVEGSYRD AVSMYARAGI DDISVENKPL YQMRLLSEAF VIKGLSLERL PNSVASHIRL TEREEEVVAC FERASWVAQV FLQELEKTSN NSTSRHLKGS LSPDYELSYF LEAALQSAYV KNLKKGNIVK GMRELREILR TVETKATQNF KVVAAKHLAG VLLHSLSEDC YWSPLSHPLP EFMNKEENSF VTQTLRKPHL YEGDNLYCPK DNIEEALLLL LISESMATRD VVLSRAPEQA EDRKVSLQNA SAIYDLLSIT LGRRGQYVML SECLERAMKC AFGEFHLWYQ VALSMVACGK SAYAVSLLRE CMKLQPSDPT VPLMAAKVCI GSLHWLEEAE HFATVVIGLG EEAGESLPKG YLALGLTYSL QATDATLKSK QDELHRKALQ TLERARELAP DDPQIIFYVA LQLALVRQIS SAMERLQEAL TMCRDDANAL HLLALLFSAQ KYYQHALDVI NMAITEHPEN FNLMFTKVKL EQVLKGPEEA LVTCRQMLRL WQTLYNFSQL GGLEKDGSFE GLTVKKQNGI HLTLPDAHDA DSGSRRASSI AASRLEEAMS ELTLTTSVLK QGPMQLWTTL EQIWLQAAEL FMEQRQLKEA GFCIQEAAGL FPTSHSVLYM RGRLAEVKGS FEEAKQLYKE ALTVNPDGVR IMHSLGLMLS QLGHKSLAQK VLRDAVERQS TFHEAWQGLG EVLQDQGQNE AAVDCFLTAL ELEASSPVLP FSIIAREL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Alternative Name: Ttc7a

Background: Tetratricopeptide repeat protein 7A (TPR repeat protein 7A),FUNCTION: Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity). In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions (By similarity). {ECO:0000250|UniProtKB:Q86TV6, ECO:0000250|UniProtKB:Q9ULT0}.

Molecular Weight: 96.2 kDa

UniProt: Q8BGB2

AlphaFold: Q8BGB2

Pathways: Transition Metal Ion Homeostasis