EXOC6 Protein (AA 1-802) (His tag)

Catalog No. ABIN7564695

Recombinant EXOC6 protein expressed in HEK-293 Cells.

Quick Overview for EXOC6 Protein (AA 1-802) (His tag) (ABIN7564695)

Target: EXOC6 (Exocyst Complex Component 6 (EXOC6))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-802

Purification tag / Conjugate: This EXOC6 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Exoc6 Protein expressed in mammalian cells.

Sequence: MAESCEALGT VPEHERILQE IESTDTACVG PTLRSVYDDQ PNAHKKFMEK LDACIRNHDK EIEKMCNFHH QGFVDAITEL LKVRADAEKL KVTDTNRRFQ DAGKEVIIQT EDIIRCRIQQ RNITTVVEKL QLCLPVLEMY SKLKEQMSMK RYYSALKTME QLENVYFPRV SQYRFCQLMM ETLPKLREDM MNYCMSDLTY GLESIRKHSD KIGEAAMKQA QQQKSFSVAL QKQNNMRFGK NMHVNNDRIL EEKSDVIPKH ALEEEAENDE EVLTVQDLVD FSPVYRCLHI YSALGDEETF ENYYRKQRKK QARLVLQPQS SVHETVDGYR RYFTQIVGFF VVEDHILHVT QGLVTRVYTE ELWNMALSKI IAVLRAHSSY CTDPDLVLEL KNLIVIFADT LQGYGFPVNR LFDLLFEIRD QYNETLLKKW AGIFRDIFEE DNYSPIPIGS EEEYKVVISR FPFQDPDLEK QSFPKKFPMS QSVPLIYIQV KEFIYASLKF SESLHRSSTE IDDMLRKSTN LLLTRILSSC LLNLIRKPHI GLTELVQIII NTTHLEQACK YLEDFITNIT NISQETVHTT RLYGLSTFKD ARHAAEGEIY TKLNQKIDEF VQLADYDWTM AESDGRASGY LMDLINFLRS IFQVFTHLPG KVAQTACMSA CQHLSTSLMQ MLLDSELKQI SMGAVQQFNL DVIQCELFAS SEPVPGFQGD TLQLAFIDLR QLLDLFMVWD WSTYLADYGQ PASKYLRVNP HAALTLLEKM KDTSKKNNIF AQFRKNDRDR QKLIETVVRQ LRGLVTGMSQ HT Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: EXOC6 (Exocyst Complex Component 6 (EXOC6))

Alternative Name: Exoc6

Background: Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1),FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. {ECO:0000250}.

Molecular Weight: 93.1 kDa

UniProt: Q8R313

AlphaFold: Q8R313

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis