BomoTx Toxin (Active) Protein

Catalog No. ABIN7582348

Native BomoTx Toxin protein expressed in Bothrops moojeni (Brazilian lancehead pit viper).

Quick Overview for BomoTx Toxin (Active) Protein (ABIN7582348)

Target: BomoTx Toxin

Protein Type: Native

Biological Activity: Active

Origin: Bothrops moojeni (Brazilian lancehead pit viper)

Source: Bothrops moojeni (Brazilian lancehead pit viper)

Purity: ≥99 % (HPLC)

Product Details

Purpose: BomoTx Toxin

Sequence: SLVELGKMIL QETGKNPVTS YGAYGCNCGV LGRGKPKDAT DRCCYVHKCC YKKLTDCNPK KDRYSYSWKD KTIVCGENNS CLKELCECDK AVAICLRENL DTYNKKYKNN YLKPFCKKAD PC

Specificity: Toxin target: P2X2/P2X3 receptors

Sterility: Sterile filtered

Biological Activity Comment: BomoTx Toxin excites sensory neurons via ATP release and consequent activation of P2X2 and/or P2X3 receptors.

Application Details

Application Notes: Antigen Preadsorption Control: 1 μM

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. The product is readily soluble in high-quality pure water at micromolar to millimolar concentrations (typically 100 μM to 1  mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x the final working concentration. Divide the stock solution into small, single-use aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.

Buffer: Lyophilized from a filtered ammonium acetate solution. May contain residual acetate ions.

Handling Advice: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture

Storage: -20 °C

Storage Comment: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.

Target Details

Target: BomoTx Toxin

Background: A somatosensory, pain inducing neuron stimulator, indirect P2X2/P2X3 receptors agonist

Molecular Weight: 13834 Da

UniProt: A0A1S5XW05