ApoE3 Protein (AA 19-317) (Biotin,His-Avi Tag)
Quick Overview for ApoE3 Protein (AA 19-317) (Biotin,His-Avi Tag) (ABIN7583224)
Target
Protein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 19-317
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Purification tag / Conjugate
- This ApoE3 protein is labelled with Biotin,His-Avi Tag.
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Purpose
- Biotinylated Human APOE3/Apolipoprotein E Protein
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Sequence
- Lys19-His317
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Characteristics
- Recombinant Biotinylated Human APOE3/Apolipoprotein E Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Lys19-His317.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Biotinylated Human APOE3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Apolipoprotein E3 (ApoE3) (AA 19-317) (Active) protein (His tag)
ApoE3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 85 % as determined by HPLC Active
Apolipoprotein E3 (ApoE3) (AA 19-317) (Active) protein (Biotin,His tag)ApoE3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE Active
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22 μm filtered solution in PBS, 200 mM L-arginine ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- ApoE3 (Apolipoprotein E3 (ApoE3))
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Alternative Name
- APOE3
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Background
- Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
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Molecular Weight
- 37.66 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
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UniProt
- P02649
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Pathways
- Regulation of Cell Size, Lipid Metabolism
Target
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