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LY9 Protein (AA 251-452) (mFc Tag)

Recombinant LY9 protein expressed in HEK-293 Cells.
Catalog No. ABIN7583257
$522.92
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
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Quick Overview for LY9 Protein (AA 251-452) (mFc Tag) (ABIN7583257)

Target

See all LY9 (CD229) Proteins
LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 14
  • 6
Human

Source

  • 7
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 251-452

    Purification tag / Conjugate

    This LY9 protein is labelled with mFc Tag.

    Purpose

    Human CD229/SLAMF3 Protein

    Sequence

    Gly251-Asn452

    Characteristics

    Recombinant Human CD229/SLAMF3 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Gly251-Asn452.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Human CD229 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human CD229 is greater than 95% as determined by SEC-HPLC.
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).

    Storage

    -80 °C

    Storage Comment

    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

    Alternative Name

    CD229

    Background

    CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells.

    Molecular Weight

    48.04 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

    UniProt

    Q9HBG7

    Pathways

    BCR Signaling
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