LY9 Protein (AA 251-452) (mFc Tag)
Quick Overview for LY9 Protein (AA 251-452) (mFc Tag) (ABIN7583257)
Target
See all LY9 (CD229) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 251-452
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Purification tag / Conjugate
- This LY9 protein is labelled with mFc Tag.
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Purpose
- Human CD229/SLAMF3 Protein
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Sequence
- Gly251-Asn452
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Characteristics
- Recombinant Human CD229/SLAMF3 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Gly251-Asn452.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Human CD229 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human CD229 is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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Alternative Name
- CD229
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Background
- CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells.
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Molecular Weight
- 48.04 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
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UniProt
- Q9HBG7
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Pathways
- BCR Signaling
Target
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