CEACAM8 Protein (AA 35-320) (His tag)

Catalog No. ABIN7677478

This Recombinant CEACAM8 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for CEACAM8 Protein (AA 35-320) (His tag) (ABIN7677478)

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 35-320

Purification tag / Conjugate: This CEACAM8 protein is labelled with His tag.

Sequence: QLTIEAVPSN AAEGKEVLLL VHNLPQDPRG YNWYKGETVD ANRRIIGYVI SNQQITPGPA YSNRETIYPN ASLLMRNVTR NDTGSYTLQV IKLNLMSEEV TGQFSVHPET PKPSISSNNS NPVEDKDAVA FTCEPETQNT TYLWWVNGQS LPVSPRLQLS NGNRTLTLLS VTRNDVGPYE CEIQNPASAN FSDPVTLNVL YGPDAPTISP SDTYYHAGVN LNLSCHAASN PPSQYSWSVN GTFQQYTQKL FIPNITTKNS GSYACHTTNS ATGRNRTTVR MITVSD

Purification: > 95% by SDS - PAGE

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Alternative Name: CD66b/CEACAM8

Background: CEACAM-8, also known as CD66b, is a cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. It mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Its main function is cell adhesion, cell migration, and pathogen binding. However, its biological functions are largely unknown in eosinophils. It has been reported that CEACAM-8 is highly expressed on the surface of human peripheral blood eosinophils isolated from healthy individuals and used as granulocyte marker. Recombinant human CEACAM-8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 32.3kDa (292aa)

NCBI Accession: NP_001807