Ephrin A3 Protein (EFNA3) (AA 23-214) (hIgG-His-tag)
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- Target See all Ephrin A3 (EFNA3) Proteins
- Ephrin A3 (EFNA3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-214
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Ephrin A3 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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QGPGGAL GNRHAVYWNS SNQHLRREGY TVQVNVNDYL DIYCPHYNSS GVGPGAGPGP GGGAEQYVLY MVSRNGYRTC NASQGFKRWE CNRPHAPHSP IKFSEKFQRY SAFSLGYEFH AGHEYYYIST PTHNLHWKCL RMKVFVCCAS TSHSGEKPVP TLPQFTMGPN VKINVLEDFE GENPQVPKLE KSISG - Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product EFNA3 Protein
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Ephrin A3 (EFNA3) (AA 23-206) protein (Fc Tag)
EFNA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ephrin A3 (EFNA3) (AA 23-213) protein (Fc Tag)EFNA3 Origin: Human, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ephrin A3 (EFNA3) (AA 23-213) protein (His tag)EFNA3 Origin: Human, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ephrin A3 (EFNA3) (AA 1-238) protein (GST tag)EFNA3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ephrin A3 (EFNA3) (AA 23-214) protein (His tag)EFNA3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- Ephrin A3 (EFNA3)
- Alternative Name
- Ephrin-A3 (EFNA3 Products)
- Background
- Ephrin-A3, also known as EFNA3, is a member of the ephrin family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. This protein activates EphA4 on hippocampal neurons to regulate dendritic spine morphology and long term potentiation. The same interaction induces reverse signaling through it to regulate glutamate uptake by the astrocyte and the availability of glutamate in the synapse. Astrocyte-expressed Ephrin-3 also interacts with EphA7 to inhibit the proliferation of neural progenitor cells. Recombinant human Ephrin-A3, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 48.7 kDa (434aa)
- NCBI Accession
- NP_004943
- Pathways
- RTK Signaling
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