Ephrin A3 Protein (EFNA3) (AA 23-211) (His tag)

Catalog No. ABIN1096579

Product Details

Target: Ephrin A3 (EFNA3)

Protein Type: Recombinant

Protein Characteristics: AA 23-211

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Ephrin A3 protein is labelled with His tag.

Purpose: Recombinant Human Ephrin-A3/EFNA3(C-6His)

Sequence: QGPGGALGNR HAVYWNSSNQ HLRREGYTVQ VNVNDYLDIY CPHYNSSGVG PGAGPGPGGG AEQYVLYMVS RNGYRTCNAS QGFKRWECNR PHAPHSPIKF SEKFQRYSAF SLGYEFHAGH EYYYISTPTH NLHWKCLRMK VFVCCASTSH SGEKPVPTLP QFTMGPNVKI NVLEDFEGEN PQVPKLEKSV DHHHHHH

Characteristics: Recombinant Human Ephrin-A3 produced by transfected human cells is a secreted protein with sequence (Gln23-Ser211) of Human EFNA3 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Ephrin A3 (EFNA3)

Alternative Name: ephrin-a3 (EFNA3 Products)

Synonyms: efna3 Protein, D160 Protein, ephrin-A3 Protein, zgc:100772 Protein, AW494418 Protein, EFL-2 Protein, Ehk1-L Protein, Epl3 Protein, LERK-3 Protein, MGC64593 Protein, EFL2 Protein, EPLG3 Protein, LERK3 Protein, ephrin A3 Protein, ephrin-A3b Protein, ephrin A3 L homeolog Protein, efna3 Protein, EFNA3 Protein, efna3b Protein, Efna3 Protein, efna3.L Protein

Sub Type: Fusionprotein

Background: Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhermore, it is associated with tumor growth and metastasis.
Alternative Names: Ephrin-A3, EFL-2, EHK1 Ligand, EHK1-L, EPH-Related Receptor Tyrosine Kinase Ligand 3, LERK-3, EFNA3, EFL2, EPLG3, LERK3

Molecular Weight: 22.25 kDa

UniProt: P52797

Pathways: RTK Signaling