Claudin 4 Protein (CLDN4) (DYKDDDDK Tag,Strep Tag)
Quick Overview for Claudin 4 Protein (CLDN4) (DYKDDDDK Tag,Strep Tag) (ABIN7596563)
Target
See all Claudin 4 (CLDN4) ProteinsProtein Type
Origin
Source
Application
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Purification tag / Conjugate
- This Claudin 4 protein is labelled with DYKDDDDK Tag,Strep Tag.
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Purpose
- Human CLDN4-Strep full length protein-synthetic nanodisc
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Claudin 4 (CLDN4) (AA 1-210) protein (His tag)
custom-made CLDN4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 4 (CLDN4) (AA 1-209) protein (His tag)custom-made CLDN4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 4 (CLDN4) proteinCLDN4 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Claudin 4 (CLDN4) (AA 145-157) protein (Fc Tag)CLDN4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 4 (CLDN4) (AA 145-157) protein (mFc Tag)CLDN4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 4 (CLDN4) (AA 1-209) protein (GST tag)CLDN4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Comment
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- Claudin 4 (CLDN4)
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Alternative Name
- CLDN4
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Background
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CPE-R, CPER, CPETR, CPETR1, hCPE-R, WBSCR8
The protein belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. -
Molecular Weight
- The human full length CLDN4-Strep protein has a MW of 22.1 kDa
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UniProt
- O14493
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Pathways
- Hepatitis C
Target
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