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Claudin 4 Protein-VLP (CLDN4) (AA 1-209)

CLDN4 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC
Catalog No. ABIN7504302
  • Target See all Claudin 4 (CLDN4) Proteins
    Claudin 4 (CLDN4)
    Protein Type
    VLP
    Protein Characteristics
    AA 1-209
    Origin
    • 9
    • 2
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purpose
    Human Claudin 4 Protein-VLP
    Sequence
    Met1-Val209
    Characteristics
    Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.
    Purity
    > 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CLDN4 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Claudin 4 (CLDN4)
    Alternative Name
    Claudin 4 (CLDN4 Products)
    Synonyms
    CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein
    Background
    Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
    Molecular Weight
    23.31 kDa.
    UniProt
    O14493
    Pathways
    Hepatitis C
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