Glutamate Receptor 3 Protein (DYKDDDDK Tag,Strep Tag)
-
- Target See all Glutamate Receptor 3 (GRIA3) Proteins
- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
- Protein Type
- Synthetic Nanodisc
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Glutamate Receptor 3 protein is labelled with DYKDDDDK Tag,Strep Tag.
- Application
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- Purpose
- Human GRIA3-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product GRIA3 Protein
-
Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 1-144) protein (GST tag)
GRIA3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 151-250), (partial) protein (His-SUMO Tag)GRIA3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 151-250), (partial) protein (His tag)GRIA3 Origin: Human Host: Yeast Recombinant > 90 % SDS
-
- Comment
-
Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
- Alternative Name
- GRIA3 (GRIA3 Products)
- Background
-
GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94, MRXSW
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length GRIA3-Strep protein has a MW of 101.2 kDa
- UniProt
- P42263
- Pathways
- PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
-
