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FGF1 Protein (AA 16-155) (Fc Tag)

This Recombinant FGF1 protein is produced in HEK-293 Cells.
Catalog No. ABIN7597309

Quick Overview for FGF1 Protein (AA 16-155) (Fc Tag) (ABIN7597309)

Target

See all FGF1 Proteins
FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Protein Type

Recombinant

Origin

  • 22
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 29
  • 10
  • 4
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
  • Protein Characteristics

    AA 16-155

    Purification tag / Conjugate

    This FGF1 protein is labelled with Fc Tag.

    Purpose

    Recombinant human FGF1 Protein with C-terminal human Fc tag

    Sequence

    FGF1(Phe16-Asp155) hFc(Glu99-Ala330)
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  • Application Notes

    Extracellular Domain Proteins (ECD) can be used as:
    • Immunogens for antibody drug development
    • Reagents used for CAR-T positive cell monitoring
    • Reagents for antibody screening and functional testing
    • Reagents for antibody affinity measurement

    Comment

    The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

    Alternative Name

    FGF1

    Background

    AFGF, ECGF, FGFA, ECGFA, ECGFB, FGF-1, HBGF1, HBGF-1, GLIO703, ECGF-beta, FGF-alpha
    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]

    Molecular Weight

    predicted molecular mass of 42.0 kDa after removal of the signal peptide.

    UniProt

    P05230

    Pathways

    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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