FGF1 Protein (AA 16-155) (Fc Tag)
Quick Overview for FGF1 Protein (AA 16-155) (Fc Tag) (ABIN7597309)
Target
See all FGF1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 16-155
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Purification tag / Conjugate
- This FGF1 protein is labelled with Fc Tag.
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Purpose
- Recombinant human FGF1 Protein with C-terminal human Fc tag
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Sequence
- FGF1(Phe16-Asp155) hFc(Glu99-Ala330)
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
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Alternative Name
- FGF1
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Background
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AFGF, ECGF, FGFA, ECGFA, ECGFB, FGF-1, HBGF1, HBGF-1, GLIO703, ECGF-beta, FGF-alpha
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009] -
Molecular Weight
- predicted molecular mass of 42.0 kDa after removal of the signal peptide.
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UniProt
- P05230
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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